Video: The PCR Song (with lyrics)

Addendum: There’s a follow up to the PCR song – Bio-Rad’s GTCA Song.

PCR = Polymerase Chain Reaction, used for gene amplication for work with DNA/RNA.

It’s actually an advertisement for PCR machines by Bio-Rad, and damn it’s good.

Lyrics below.

The PCR Song by Scientists for Better PCR

There was a time when to amplify DNA,
You had to grow tons and tons of tiny cells.
(Oooh) Then along came a guy named Dr. Kary Mullis,
Said you can amplify in vitro just as well.

Just mix your template with a buffer and some primers,
Nucleotides and polymerases too.
Denaturing, annealing, and extending,
Well it’s amazing what heating and cooling and heating will do.

[Chorus]
PCR when you need to detect mutation (detect mutation)
PCR when you need to recombine (recombine)
PCR when you need to find out who the daddy is (who’s your daddy?)
PCR when you need to solve a crime (solve a crime)
[x2]

[Advertisement]
(PCR) To all the scientists out there doing PCR, Bio-Rad salutes you with the all-new 1000 series thermal cycling platform.

52 responses to this post.

  1. Posted by Cindy on January 19, 2008 at 11:44 pm

    Yeah, I think it is real great, and I really salute Bio-Rad for coming up with such a creative ad for PCR machines :)

    Reply

  2. Posted by endoderm on January 21, 2008 at 1:56 pm

    it is a really good song!

    Reply

  3. Posted by Adakatia on February 6, 2008 at 12:49 am

    Excellent, its really a science popularization!
    Congratulations!

    Reply

  4. Posted by Mia on February 14, 2008 at 6:45 am

    Great! Even our lecturer from molecular science showed it to us just before the exam :P

    Reply

  5. Posted by flavina on February 15, 2008 at 5:47 am

    PCR rocksssss!!!!!!!!

    Reply

  6. Posted by Tasse on March 7, 2008 at 2:51 am

    The next album must be named : “The RT-PCR song”

    very good!!!

    Reply

  7. Posted by E.N.N on March 13, 2008 at 7:56 pm

    Great! It’s really useful for my exam on Molecular Biotechnology.

    Reply

  8. Posted by Fabricio on March 26, 2008 at 7:24 am

    Really Great!!!! They must gain some prize for the creative!

    Reply

  9. Posted by butcher on May 17, 2008 at 8:57 pm

    tres bien… very emotional and funny too… well done

    Reply

  10. Posted by Michał on June 11, 2008 at 3:22 pm

    PCR when you need to check correctness cloning… :P

    Reply

  11. Posted by Steffi on July 23, 2008 at 5:12 am

    sooooooo genial!!!
    ich krieg den Song nictmehr aus meinem Hirn.
    einfach genial Aufgemacht

    Reply

  12. Posted by David Paul on August 25, 2008 at 9:27 am

    I want a green lightsaber

    Reply

  13. Posted by Crick Smellsington on August 25, 2008 at 9:51 am

    This song changed my life

    Reply

  14. Posted by bio-student on August 26, 2008 at 1:37 am

    I love this song! It’s amazing!

    Reply

  15. Posted by Guille on September 5, 2008 at 5:10 am

    Rasco deja de molestar

    Reply

  16. Posted by Rasco on September 5, 2008 at 5:25 am

    Si, yo que se que son unos aparatos importantes, pero se rieron un poco? De los comentarios de la gente aunque sea….

    Reply

  17. Posted by monis on September 5, 2008 at 10:36 pm

    it is so funny

    is there any thing else like this

    Reply

  18. Great sonfg if you like PCR.

    Reply

  19. Posted by Moses Grimaldo on October 16, 2008 at 10:00 am

    Guess what is going in this friday’s seminar!!
    The carriying of the ThCy was a blast jajaja.

    Reply

  20. Posted by n00rul on January 19, 2009 at 12:53 pm

    very very entertaining and educating too! excellent job! 2 thumbs up for bio-rad!

    Reply

  21. Posted by saurabha on March 15, 2009 at 12:30 am

    I love this song! It’s amazing!

    Reply

  22. Posted by saurabha srivastava on March 15, 2009 at 12:31 am

    I love this song! It’s amazing! I love this song! It’s amazing!

    Reply

    • Posted by Crick Smellsington on October 22, 2009 at 11:55 am

      saurabha srivastava, how about that name.. pretty hard to say. Where is the name from?

      I am awaiting your reply.

      Reply

      • Posted by Saurabha srivastava on October 28, 2009 at 10:00 pm

        Hi Crick Smellsington,
        i am from India, my name is pretty hard by meaning is very nice.
        what about you?

        waiting for your reply.

  23. Posted by Billi on March 15, 2009 at 12:38 am

    i LOVE this song tooooooooo much :):)

    Reply

  24. Posted by saurabha srivastava on October 22, 2009 at 12:03 pm

    Yo Crick Smellsington, what’s poppin’? The name’s fro India Bruvahhh. Smellsington.. pretty shit name you cracker. What kinda of a clowns are you parents?

    Reply

  25. Posted by saurabha srivastava on October 22, 2009 at 12:05 pm

    hey shuddup crackahhh. I’ll shank you. Where you from!?

    Reply

  26. Posted by saurabha srivastava on October 22, 2009 at 12:08 pm

    YEAH I WANNA FIGHT. AND I’M FROM DC AS WELL!!

    Meet me Pimmit Hills in half an hour muthafucka.

    Reply

  27. Posted by Crick Smellsington on October 22, 2009 at 12:08 pm

    ok oobra shoobra! you’r on. You’re gonna die.

    Reply

  28. Posted by Carolina on February 1, 2010 at 1:15 am

    Love this song! It makes me laugh so much ^^

    Reply

  29. Posted by hieu on September 9, 2010 at 5:20 pm

    good song :))

    Reply

  30. Posted by erika on December 15, 2011 at 9:36 pm

    AWESOME!!! CONGRATULATIONS TO ALL OF YOU!

    Reply

  31. […] we come to the end, here is one last pick for today: a commercial for a PCR machine (full lyrics). Don’t worry … it’s much more fun than it […]

    Reply

  32. Posted by Rose on March 6, 2012 at 12:19 am

    I love when art and science mix together :) In this way, scientific progress has a new meaning and it is put out of sterile laboratories and epruvets. It shows also how we love our work. I congradulate artists that performed so exellent our love to PCR. Thank you.

    Reply

  33. Posted by Sam on April 6, 2012 at 10:55 pm

    I show this video to everyone I know, especially those in the biology field. ^^

    Reply

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